Core Facilities at Queen Mary University of London are run by experienced staff who are able to help with experimental design, troubleshooting and data interpretation. In some facilities, equipment is available for researchers to use, while in other facilities your experiment is carried out for you according to a service level agreement. All facilities encourage interaction between users and members of the core facility.
Facilities at WHRI include:
Cryopreservation Transgenic Facility
The Cryopreservation Facility at the WHRI offers the possibility of freezing murine embryos and sperm from transgenic lines through cryopreservation. Cryopreservation is an advantageous process for safely preserving murine embryos and sperm at very low temperatures easily rederive /cryorecover them. It significantly reduces costs associated with colony maintenance, functions as a backup of transgenic lines, it complies with Home Office 3Rs (refinement, reduction and replacement).
We work with academic (with and without QMUL affiliation) and corporate partners, on a not for profit basis, to achieve their genomics research aims. Our model is to provide a custom service, offering advice on design and interpretation if required.
Flow Cytometry is a versatile technique enabling high throughput analysis and cell separation. Using fluorescent proteins, dyes, and fluorescently labelled probes we can perform cellular phenotyping, functional assays, cell cycle analysis, intracellular protein studies e.g. cytokines and transcription factors, and more.
The WHRI is equipped with core microscopy facilities available to all labs. The facility includes a recently purchased inverted Zeiss 880 confocal microscope with Airy Scan, an inverted Zeiss 800 microscope, upright Leica SP5 and SP8 confocal microscopes, a time lapse epifluorescent microscopes and multiple brightfield/epifluorescent microscopes.
Lipid Mediator Unit
A QMUL Core Service that provides the instrumentation and expertise to investigate endogenous protective mechanisms that may become disregulated in disease with a focus on bioactive lipid mediators.