Image - Barts and The London logo and link to home page Image - divider Image - divider
 
  Image - Title and link to homepage
Image - Heart model cross section and graph
  link Home

link Clinical Links

link Research link Courses link News/events link Staff link Contact us
 
Translational Medicine and Therapeutics

Academic Staff :

 

 

Research within the Centre focuses on the discovery of basic mechanisms and development of novel medicines to reduce the number of people suffering and ultimately dying from cardio-vascular disease and shock.

Why cardiovascular disease? Since the turn of the last century, cardiovascular disease (including diabetes, chronic kidney disease as well as heart attacks and heart failure) has been the leading cause of death in the United Kingdom.

Why Shock? Shock can be defined as a “progressive failure of the circulation to provide blood and oxygen to vital organs of our body”. The most common causes of shock are the contamination of blood with bacteria resulting in systemic infection and ultimately shock (septic shock) and the severe blood loss associated with trauma (haemorrhagic shock). Despite improvements in intensive care medicine, the mortality of shock remains very high (40-50%).

The therapeutic approaches currently being researched within our Centre are wide-ranging and include the use of stem cells to regenerate tissue, the development of novel dietary strategies (i.e. to mimic the benefits of red wine consumption) and the development of novel drugs which reduce the excessive local and systemic inflammation associated with a number of cardiovascular disorders and shock. This is complemented by research on new diagnostic tests to identify people at risk of cardiovascular disease at an earlier stage.
 

 

 

 

Our research would not be possible without the assistance of the following organisations:

 

Top

 

 
Top
 
by Web Editor. © Queen Mary, University of London 2004
William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ