Anthony Mathur

Clinical Senior Lecturer

I divide my time equally between clinical work and basic science with the aim of conducting translational research. My basic science interests have evolved from my PhD undertaken at UCL where I gained an understanding of platelet and stem cell biology as well as cellular bioenergetics. These interests are now consolidated in my work looking at the mechanisms by which stem cells may improve cardiac function.

My clinical work is directed at interventional cardiology and the management of patients with heart failure and angina who have failed conventional therapy. I am Secretary of the ESC Task force on Stem cells in cardiovascular disease and also Chair the clinical group of the British Cardiac stem cells collaborative set up by Professor John Martin.

These roles have enabled me to design a series of clinical trials that will address some of the outstanding issues surrounding the use of stem cells to treat cardiovascular disease. I also have a major interest in the use of advanced cardiac imaging for translational research and have the role of Lead Clinician for Advanced Cardiac Imaging. 

Summary of Research

Anthony Mathur leads a collaborative group with Prof. John Martin (UCL) seeking to address the role of stem cells in the treatment of cardiovascular disease. This partnership has lead to the establishment of the largest series of  clinical trials translating the interesting results produced by basic experimentation into relevant therapeutic approaches in man. He now is the PI in one of the first Phase III clinical trials of cell therapy in acute myocardial infarction.

The clinical work is also underpinned by a collaboration with Prof Suzuki (WHRI) to understand the basic mechanisms that are involved in stem cell repair of the heart.

Anthony Mathur’s other research interest is in advanced cardiac imaging and in particular its use to examine mechanistic aspects of translational research. He has assembled a state of the art collection of advanced imaging hardware (cardiac MR, PET/CT, cardiac CT, nuclear perfusion and advanced echo) that is strategically run through a joint imaging board that he chairs.

Overall Professor Mathur’s research in interventional cardiology is targeted at the no-option patient with the aim of developing new techniques and devices to treat patients that fall outside the remit of current recognised therapies

Key Publications

Mathur A, Martin JF (2004). Stem cells and repair of the heart.. Lancet Vol.364, (9429) 183-192.

Martin JF, Kristensen SD, Mathur A et al. (2012). The causal role of megakaryocyte-platelet hyperactivity in acute coronary syndromes. NATURE REVIEWS CARDIOLOGY Vol.9, (11) 1759-5002 658-670. 

Bartunek J, Dimmeler S, Drexler H et al. (2006). The consensus of the task force of the European Society of Cardiology concerning the clinical investigation of the use of autologous adult stem cells for repair of the heart. EUR HEART J Vol.27, (11) 0195-668X 1338-1340. 10.1093/eurheartj.ehi793

Fisher SA, Dorée C, Brunskill SJ et al. (2013). Bone Marrow Stem Cell Treatment for Ischemic Heart Disease in Patients with No Option of Revascularization: A Systematic Review and Meta-Analysis.. PLoS One Vol.8, (6) e64669-.

Clifford DM, Fisher SA, Brunskill SJ et al. (2012). Long-term effects of autologous bone marrow stem cell treatment in acute myocardial infarction: factors that may influence outcomes.. PLoS One Vol.7, (5) e37373 10.1371/journal.pone.0037373

PubLists Publications

Jones DA, Gallagher S, Rathod KS et al. (2013). Contemporary analysis of incidence and outcomes of stent thrombosis presenting as ST elevation myocardial infarction in a primary percutaneous coronary intervention cohort.. Am J Cardiol Vol.112, (9) 1347-1354.
10.1016/j.amjcard.2013.07.002
Jones DA, Gallagher S, Rathod K et al. (2013). Clinical outcomes after myocardial revascularization according to operator training status: cohort study of 22 697 patients undergoing percutaneous coronary intervention or coronary artery bypass graft surgery.. Eur Heart J Vol.34, (37) 2887-2895.
10.1093/eurheartj/eht161
Rathod KS, Jones DA, Rathod VS et al. (2013). Prognostic impact of anaemia on patients with ST-elevation myocardial infarction treated by primary PCI.. Coron Artery Dis Vol., () -.
10.1097/MCA.0000000000000038
Rossi A, Dharampal A, Wragg A et al. (2013). Diagnostic performance of hyperaemic myocardial blood flow index obtained by dynamic computed tomography: does it predict functionally significant coronary lesions?. Eur Heart J Cardiovasc Imaging Vol., () -.
10.1093/ehjci/jet133
Jones DA, Choudry F, Mathur A (2013). Almanac 2012, cell therapy in cardiovascular disease: the journals present selected research that has driven recent advances in clinical cardiology.. Anadolu Kardiyol Derg Vol., () -.
10.5152/akd.2013.167
Jones DA, Choudry F, Mathur A (2013). Almanac 2012: cell therapy in cardiovascular disease. the national society journals present selected research that has driven recent advances in clinical cardiology.. Hellenic J Cardiol Vol.54, (3) 159-167.
Jones DA, Rathod KS, Gallagher S et al. (2013). Deployment of drug-eluting stents for isolated proximal lad disease is associated with lower major adverse cardiac events and no increase in stent thrombosis when compared with bare metal stents: a 5-year observational cohort study.. Catheter Cardiovasc Interv Vol.81, (6) E237-E244.
10.1002/ccd.24513
Pain TE, Jones DA, Rathod KS et al. (2013). Influence of female sex on long-term mortality after acute coronary syndromes treated by percutaneous coronary intervention: a cohort study of 7304 patients.. Coron Artery Dis Vol.24, (3) 183-190.
10.1097/MCA.0b013e32835d75f0
Choudhury TR, Mathur A (2013). The birth of 'regenerative pharmacology': a clinical perspective.. Br J Pharmacol Vol.169, (2) 239-246.
10.1111/bph.12128
Jones DA, Khambata RS, Mathur A et al. (2013). Sodium nitrite promotes the viability and proliferation of endothelial cells but inhibits the growth of smooth muscle cells under hypoxia. NITRIC OXIDE-BIOLOGY AND CHEMISTRY Vol.31, () 1089-8603 S22-S22.
10.1016/j.niox.2013.02.024
Jones DA, Choudry F, Mathur A (2013). Almanac 2012: Cell therapy in cardiovascular disease. The national society journals present selected research that has driven recent advances in clinical cardiology.. Rev Port Cardiol Vol.32, (4) 351-358.
10.1016/j.repc.2013.02.001
Mozid AM, Jones D, Arnous S et al. (2013). The effects of age, disease state, and granulocyte colony-stimulating factor on progenitor cell count and function in patients undergoing cell therapy for cardiac disease.. Stem Cells Dev Vol.22, (2) 216-223.
10.1089/scd.2012.0139
Fisher SA, Dorée C, Brunskill SJ et al. (2013). Bone Marrow Stem Cell Treatment for Ischemic Heart Disease in Patients with No Option of Revascularization: A Systematic Review and Meta-Analysis.. PLoS One Vol.8, (6) e64669-.
10.1371/journal.pone.0064669
Jones DA, Gallagher S, Rathod KS et al. (2013). Contemporary analysis of incidence and outcomes of stent thrombosis presenting as ST elevation myocardial infarction in a primary percutaneous coronary intervention cohort. American Journal of Cardiology Vol.112, (9) 0002-9149 1347-1354.
Rathod KS, Jones DA, Gallagher SM et al. (2013). Out-of-hours primary percutaneous coronary intervention for ST-elevation myocardial infarction is not associated with excess mortality: a study of 3347 patients treated in an integrated cardiac network.. BMJ Open Vol.3, (6) -.
10.1136/bmjopen-2013-003063
Jones DA, Andiapen M, Van-Eijl TJ et al. (2013). The safety and efficacy of intracoronary nitrite infusion during acute myocardial infarction (NITRITE-AMI): study protocol of a randomised controlled trial.. BMJ Open Vol.3, (4) -.
10.1136/bmjopen-2013-002813
MATHUR A, Iglesias D, Tapponnier M et al. (2012). [Cell-based regenerative therapy in cardiology: the future at present]. Rev Med Suisse Vol.365, (8) 2364-2369.
Jones DA, Rathod KS, Howard JP et al. (2012). Safety and feasibility of hospital discharge 2 days following primary percutaneous intervention for ST-segment elevation myocardial infarction.. Heart Vol.98, (23) 1722-1727.
10.1136/heartjnl-2012-302414
MATHUR A, Schwartz CG, Olsson AG et al. (2012). Effects of dalcetrapib in patients with a recent acute coronary syndrome. N Engl J Med Vol.22, (367) 2089-2099.
10.1056/NEJMoa1206797
Jones DA, Choudry F, Mathur A (2012). Cell therapy in cardiovascular disease: the national society journals present selected research that has driven recent advances in clinical cardiology.. Heart Vol.98, (22) 1626-1631.
10.1136/heartjnl-2011-301540
Martin JF, Kristensen SD, Mathur A et al. (2012). The causal role of megakaryocyte–platelet hyperactivity in acute coronary syndromes.. Nat Rev Cardiol Vol.9, (11) 658-670.
10.1038/nrcardio.2012.131
Jones DA, Rathod KS, Gallagher S et al. (2012). Drug eluting stents appear superior to bare metal stents for vein graft pci in a propensity matched cohort. EUROPEAN HEART JOURNAL Vol.33, () 0195-668X 390-390.
Bromage D, Rathod KS, Jones DA et al. (2012). Drug eluting stents are associated with lower MACE rates compared to bare metal stents in small coronary arteries treated by primary PCI for STEMI. EUROPEAN HEART JOURNAL Vol.33, () 0195-668X 665-665.
Rathod VS, Gallagher SM, Rathod KS et al. (2012). Insulin dependent diabetes results in worse outcomes compared to non-insulin dependent diabetes following elective PCI. EUROPEAN HEART JOURNAL Vol.33, () 0195-668X 393-393.
Jones D, Rathod KS, Howard J et al. (2012). Is it safe to discharge patients 24 hours after uncomplicated successful primary percutaneous coronary intervention?. EUROPEAN HEART JOURNAL Vol.33, () 0195-668X 345-346.
Guttmann OP, Jones DA, Rathod K et al. (2012). Prior coronary artery bypass graft patients treated with primary percutaneous coronary intervention have higher long-term adverse event rates. EUROPEAN HEART JOURNAL Vol.33, () 0195-668X 550-551.
Pugliese F, Wragg A, Anagnostopoulos C et al. (2012). Relationship between regional hyperaemic myocardial blood flow on dynamic dual-source computed tomography and coronary artery stenosis. EUROPEAN HEART JOURNAL Vol.33, () 0195-668X 95-95.
Rathod KS, Jones DA, Gallagher SM et al. (2012). Thormbectomy and platelet glycoprotein IIb/IIIa blockade for stent thrombosis. EUROPEAN HEART JOURNAL Vol.33, () 0195-668X 549-549.
Bromage DI, Rathod KS, Jones DA et al. (2012). DRUG ELUTING STENT IMPLANTATION IS ASSOCIATED WITH LOWER MACE RATES THAN BARE METAL STENT IMPLANTATION IN PRIMARY PCI FOR ST ELEVATION MYOCARDIAL INFARCTION. HEART Vol.98, () 1355-6037 A24-A24.
10.1136/heartjnl-2012-301877b.38
Guttmann OP, Jones D, Rathod K et al. (2012). DRUG ELUTING STENTS (DES) OFFER BENEFIT OVER BARE METAL STENTS (BMS) INSERTED DURING VEIN GRAFT PCI. HEART Vol.98, () 1355-6037 A23-A24.
10.1136/heartjnl-2012-301877b.37
Gallagher S, Hassan S, Jones DA et al. (2012). IMPACT OF CONTRAST-INDUCED NEPHROPATHY UPON SHORT AND LONG-TERM OUTCOMES OF PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION UNDERGOING PRIMARY PERCUTANEOUS CORONARY INTERVENTION. HEART Vol.98, () 1355-6037 A70-A70.
10.1136/heartjnl-2012-301877b.124
Rathod KS, Gallagher SM, Hassan S et al. (2012). INSULIN DEPENDENT DIABETES RESULTS IN WORSE OUTCOMES COMPARED TO NON-INSULIN DEPENDENT DIABETES FOLLOWING CORONARY ARTERY BYPASS GRAFT SURGERY (CABG). HEART Vol.98, () 1355-6037 A82-A82.
10.1136/heartjnl-2012-301877b.148
Howard JP, Jones DA, Gallagher S et al. (2012). IS IT SAFE TO DISCHARGE PATIENTS 24 H AFTER UNCOMPLICATED SUCCESSFUL PRIMARY PERCUTANEOUS CORONARY INTERVENTION?. HEART Vol.98, () 1355-6037 A29-A30.
10.1136/heartjnl-2012-301877b.48
Hamshere SM, Jones DA, Akhtar M et al. (2012). PRIOR CORONARY ARTERY BYPASS GRAFT PATIENTS TREATED WITH PRIMARY PERCUTANEOUS CORONARY INTERVENTION HAVE HIGHER LONG-TERM ADVERSE EVENT RATES. HEART Vol.98, () 1355-6037 A73-A73.
10.1136/heartjnl-2012-301877b.130
Campbell NG, Kaneko M, Shintani Y et al. (2012). SIZE-DEPENDENT RETENTION OF STEM CELLS FOLLOWING INTRACORONARY INJECTION. HEART Vol.98, () 1355-6037 A67-A68.
10.1136/heartjnl-2012-301877b.119
Jones DA, Gallagher S, Rathod KS et al. (2012). SOCIO-ECONOMIC STATUS AND OUTCOME AFTER PERCUTAENOUS CORONARY INTERVENTION. HEART Vol.98, () 1355-6037 A27-A28.
10.1136/heartjnl-2012-301877b.45
Akhtar MM, Jones DA, Gallagher S et al. (2012). THROMBECTOMY AND PLATELET GLYCOPROTEIN IIB/IIIA BLOCKADE FOR STENT THROMBOSIS. HEART Vol.98, () 1355-6037 A22-A22.
10.1136/heartjnl-2012-301877b.35
Jones DA, Weerackody R, Rathod K et al. (2012). Successful Recanalization of Chronic Total Occlusions Is Associated With Improved Long-Term Survival. JACC-CARDIOVASCULAR INTERVENTIONS Vol.5, (4) 1936-8798 380-388.
10.1016/j.jcin.2012.01.012
Jones DA, Weerackody R, Rathod K et al. (2012). Successful recanalization of chronic total occlusions is associated with improved long-term survival.. JACC Cardiovasc Interv Vol.5, (4) 380-388.
10.1016/j.jcin.2012.01.012
Rathod VS, Jones DA, Rathod K et al. (2012). PRIOR CORONARY ARTERY BYPASS GRAFT PATIENTS TREATED WITH PRIMARY PERCUTANEOUS CORONARY INTERVENTION HAVE HIGHER LONG-TERM ADVERSE EVENT RATES. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol.59, (13) 0735-1097 E390-E390.
Martin-Rendon E, Clifford DM, Fisher SA et al. (2012). Long-term effect of stem cell treatment in acute myocardial infarction: what is new from 2008?. CARDIOVASCULAR RESEARCH Vol.93, () 0008-6363 S57-S57.
Jones DA, Rathod KS, Sekhri N et al. (2012). Case fatality rates for South Asian and Caucasian patients show no difference 2.5 years after percutaneous coronary intervention.. Heart Vol.98, (5) 414-419.
10.1136/heartjnl-2011-300130
Arnous S, Mozid A, Martin J et al. (2012). Bone marrow mononuclear cells and acute myocardial infarction.. Stem Cell Res Ther Vol.3, (1) 2-.
10.1186/scrt93
Iglesias JF, Tapponnier M, Hullin R et al. (2012). Cell-based regenerative therapy in cardiology: The future at present | Thérapie cellulaire régénérative en cardiologie: Le futur au présent?. Revue Medicale Suisse Vol.8, (365) 1660-9379 2364-2369.
Clifford DM, Fisher SA, Brunskill SJ et al. (2012). Long-term effects of autologous bone marrow stem cell treatment in acute myocardial infarction: factors that may influence outcomes.. PLoS One Vol.7, (5) e37373-.
10.1371/journal.pone.0037373
Clifford DM, Fisher SA, Brunskill SJ et al. (2012). Stem cell treatment for acute myocardial infarction.. Cochrane Database Syst Rev Vol.2, () CD006536-.
10.1002/14651858.CD006536.pub3.
Akhtar MM, Graham A, Jones D et al. (2011). Acute Stent Thrombosis Resulting in St Elevation Myocardial Infarction (STEMI) is Associated With Worse Clinical Outcomes Than STEMI Due to Native Coronary Thrombosis. CIRCULATION Vol.124, (21) 0009-7322 -.
Graham A, Akhtar MM, Jones D et al. (2011). Drug Eluting Stents versus Bare Metal Stents in Large Coronary Arteries During Primary Percutaneous Coronary Intervention. CIRCULATION Vol.124, (21) 0009-7322 -.
Graham A, Akhtar MM, Jones D et al. (2011). In-Stent Restenosis (ISR) is Not Simply a Benign Clinical Entity as It Presents as an Acute Coronary Syndrome (ACS) in 40% of Cases. CIRCULATION Vol.124, (21) 0009-7322 -.
Akhtar MM, Graham A, Jones D et al. (2011). Treatment of Multi-Vessel Coronary Artery Disease (CAD) in Primary Percutaneous Coronary Intervention (PPCI) for ST segment Elevation Myocardial Infarction (STEMI): Culprit Only Revascularization is Associated with Higher Major Adverse Cardiovascular Event (MACE) Rates. CIRCULATION Vol.124, (21) 0009-7322 -.
Sammut EC, Jones DA, Rathod KS et al. (2011). DES versus BMS in Large Coronary Arteries during Primary PCI. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol.58, (20) 0735-1097 B89-B90.
Jones DA, Rathod KS, Gallagher SM et al. (2011). Drug Eluting Stents in the Treatment of Isolated Proximal LAD Disease are Associated with Similar Outcomes Compared to Minimally Invasive LIMA Grafts. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol.58, (20) 0735-1097 B56-B56.
Behar JM, Abu-Own H, Sammut E et al. (2011). In-Stent Restenosis is Not a Benign Clinical Entity, Presenting As Acute Coronary Syndrome In 40% Of Cases. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol.58, (20) 0735-1097 B3-B4.
Howard JP, Buckhoree Z, Jones DA et al. (2011). No Difference In Long-term Major Adverse Cardiac Event Rates Between Paclitaxel-eluting and Sirolimus-eluting Stents. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol.58, (20) 0735-1097 B54-B54.
Guttmann O, Jones DA, Rathod K et al. (2011). Treatment Of Multivessel Coronary Artery Disease In Primary PCI for STEMI: Culprit Only Revascularisation is Associated with Higher MACE Rates. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol.58, (20) 0735-1097 B19-B19.
Choudry FA, Mathur A (2011). Stem cell therapy in cardiology.. Regen Med Vol.6, (6 Suppl) 17-23.
10.2217/rme.11.57
Jones DA, Mathur A, Smith EJ (2011). Percutaneous treatment of a chronic total occlusion for ST segment elevation myocardial infarction: an alternative in the case of early graft failure.. Heart Vol.97, (18) 1536-.
10.1136/heartjnl-2011-300261
Monney PA, Sekhri N, Burchell T et al. (2011). Acute myocarditis presenting as acute coronary syndrome: role of early cardiac magnetic resonance in its diagnosis.. Heart Vol.97, (16) 1312-1318.
10.1136/hrt.2010.204818
Rathod KS, Jones DA, Rathod VS et al. (2011). C-reactive protein as a predictor of MACE in primary PCI. EUROPEAN HEART JOURNAL Vol.32, () 0195-668X 1059-1059.
Rathod KS, Jones DA, Rathod VS et al. (2011). DES vs BMS in large coronary arteries during primary PCI. EUROPEAN HEART JOURNAL Vol.32, () 0195-668X 956-956.
Mozid A, Arnous S, Yeo C et al. (2011). Head-to-head comparison of different delivery methods of autologous bone marrow progenitor cells in chronic ischaemic heart failure. EUROPEAN HEART JOURNAL Vol.32, () 0195-668X 456-456.
Guttmann OP, Jones DA, Rathod K et al. (2011). In-stent restenosis is not simply a benign clinical entity as it presents as ACS in 40% of cases. EUROPEAN HEART JOURNAL Vol.32, () 0195-668X 747-747.
Sammut EC, Jones DA, Rathod K et al. (2011). Prognostic value of baseline renal function on long term outcome in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction. EUROPEAN HEART JOURNAL Vol.32, () 0195-668X 188-188.
Lovell MJ, Mathur A (2011). Republished review: Cardiac stem cell therapy: progress from the bench to bedside.. Postgrad Med J Vol.87, (1030) 558-564.
10.1136/pgmj.2009.192385rep
Jones D, Weerackody R, Rathod K et al. (2011). Successful recanalisation of Chronic Total Occlusions (CTO) is associated with increased long term survival. EUROPEAN HEART JOURNAL Vol.32, () 0195-668X 246-247.
Burchell TR, Davies LC, Mohiddin SA et al. (2011). The natural time-course of myocardial oedema in the first 3 months post ST-elevation MI in patients treated with primary angioplasty. EUROPEAN HEART JOURNAL Vol.32, () 0195-668X 44-45.
Pain TE, Jones DA, Rathod K et al. (2011). Treatment of multivessel coronary artery disease in primary PCI for ST elevation myocardial infarction: culprit only revascularisation is associated with higher MACE rates. EUROPEAN HEART JOURNAL Vol.32, () 0195-668X 867-867.
Arnous S, Mozid A, Mathur A (2011). The Bone Marrow Derived Adult Stem Cells for Dilated Cardiomyopathy (REGENERATE-DCM) trial: study design.. Regen Med Vol.6, (4) 525-533.
10.2217/rme.11.29
Gallagher SM, Lovell MJ, Jones D et al. (2011). A "DIRECT" TRANSFER PROTOCOL FOR PATIENTS WITH NON ST-ELEVATION MYOCARDIAL INFARCTION REDUCES TIME TO CORONARY ANGIOGRAPHY. HEART Vol.97, () 1355-6037 A5-A6.
10.1136/heartjnl-2011-300198.2
Sammut EC, Graham A, Jones DA et al. (2011). ACUTE STENT THROMBOSIS RESULTING IN ST ELEVATION MYOCARDIAL INFARCTION (STEMI) IS ASSOCIATED WITH WORSE CLINICAL OUTCOMES THAN STEMI DUE TO NATIVE CORONARY THROMBOSIS. HEART Vol.97, () 1355-6037 A13-A14.
10.1136/heartjnl-2011-300198.16
Guttmann O, Jones DA, Rathod KS et al. (2011). EARLY HOSPITAL DISCHARGE AT 48 H FOLLOWING PRIMARY PCI FOR MYOCARDIAL INFARCTION IS BOTH SAFE AND FEASIBLE. HEART Vol.97, () 1355-6037 A9-A9.
10.1136/heartjnl-2011-300198.9
Abu-Own H, Sammut E, Rathod K et al. (2011). IN-STENT RESTENOSIS PRESENTS AS AN ACUTE CORONARY SYNDROME (ACS) IN 40% OF CASES: NOT SIMPLY A BENIGN CLINICAL ENTITY. HEART Vol.97, () 1355-6037 A25-A26.
10.1136/heartjnl-2011-300198.36
Rathod KR, Jones DA, Rathod B et al. (2011). PATIENTS PRESENTING WITH ANAEMIA UNDERGOING PRIMARY PCI APPEAR AT SIGNIFICANTLY HIGHER RISK OF AN ADVERSE OUTCOME. HEART Vol.97, () 1355-6037 A15-A15.
10.1136/heartjnl-2011-300198.18
Guttmann OP, Rathod K, Rathod B et al. (2011). PROGNOSTIC VALUE OF BASELINE RENAL FUNCTION ON LONG TERM OUTCOME IN PATIENTS UNDERGOING PRIMARY PERCUTANEOUS CORONARY INTERVENTION FOR ST-ELEVATION MYOCARDIAL INFARCTION. HEART Vol.97, () 1355-6037 A31-A31.
10.1136/heartjnl-2011-300198.46
Behar JM, Jones DA, Weerackody R et al. (2011). SUCCESSFUL RECANALISATION OF CHRONIC TOTAL OCCLUSIONS IS ASSOCIATED WITH INCREASED LONG TERM SURVIVAL. HEART Vol.97, () 1355-6037 A25-A25.
10.1136/heartjnl-2011-300198.35
Guttmann OP, Jones DA, Rathod K et al. (2011). In-stent restenosis is not simply a benign clinical entity as it presents as ACS in 40% of cases. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol.183, () 1073-449X 747-747.
Mozid AM, Arnous S, Sammut EC et al. (2011). Stem cell therapy for heart diseases.. Br Med Bull Vol.98, () 143-159.
10.1093/bmb/ldr014
Choudry FA, Mathur A (2011). Stem cell therapy in cardiology. Regenerative Medicine Vol.6, (6 SUPPL.) 1746-0751 17-23.
Lovell MJ, Yasin M, Lee KL et al. (2010). Bone marrow mononuclear cells reduce myocardial reperfusion injury by activating the PI3K/Akt survival pathway.. Atherosclerosis Vol.213, (1) 67-76.
10.1016/j.atherosclerosis.2010.07.045
Lovell MJ, Mathur A (2010). Cardiac stem cell therapy: progress from the bench to bedside.. Heart Vol.96, (19) 1531-1537.
10.1136/hrt.2009.192385
Monney P, Sekhri N, Wragg A et al. (2010). Acute myocarditis presenting as acute coronary syndrome: diagnostic importance of early cardiac magnetic resonance imaging. EUROPEAN HEART JOURNAL Vol.31, () 0195-668X 37-38.
Jones D, Rathod K, Wicks E et al. (2010). An observational study comparing the long-term outcomes of Percutaneous Coronary Intervention (PCI) with stent implantation in south Asian versus Caucasian patients. EUROPEAN HEART JOURNAL Vol.31, () 0195-668X 217-217.
Rathod KS, Jones DA, Guttmann O et al. (2010). Direct transfer to a cardiac centre results in lower MACE rates compared to inter-hospital transfers for primary PCI. EUROPEAN HEART JOURNAL Vol.31, () 0195-668X 308-308.
Weerackody RP, Burchell T, Mohiddin S et al. (2010). High dose adenosine stress pefusion cardiovascular magnetic resonance (CMR) imaging for detection of coronary artery disease. EUROPEAN HEART JOURNAL Vol.31, () 0195-668X 584-585.
Rathod KS, Jones DA, Jain A et al. (2010). In vein graft PCI drug eluting stents appear to show no benefit over bare metal stents as assessed by MACE over long term follow up. EUROPEAN HEART JOURNAL Vol.31, () 0195-668X 926-927.
Jones D, Rathod K, Prinja A et al. (2010). Isolated PCI to the proximal LAD: long term follow up of DES vs BMS. EUROPEAN HEART JOURNAL Vol.31, () 0195-668X 216-216.
Rathod K, Jones D, Wicks E et al. (2010). Long term outcomes in patients with diabetes undergoing primary PCI. EUROPEAN HEART JOURNAL Vol.31, () 0195-668X 347-347.
Wong J, Dhakshinamurthy VA, Wicks E et al. (2010). Microvascular obstruction assessed by cardiovascular magnetic resonance imaging in NSTEMIs is associated with adverse outcome. EUROPEAN HEART JOURNAL Vol.31, () 0195-668X 582-582.
Jones DA, Rathod VS, Rathod KS et al. (2010). Patients under 60 years of age have excellent survival after percutaneous coronary intervention for non-ST elevation myocardial infarction. EUROPEAN HEART JOURNAL Vol.31, () 0195-668X 217-218.
Rathod KS, Jones DA, Jain A et al. (2010). Percutaneous coronary intervention performed by cardiologists in training is not associated with increased mortality. EUROPEAN HEART JOURNAL Vol.31, () 0195-668X 209-210.
Jones DA, Rathod KS, Ludman A et al. (2010). Primary angioplasty can achieve successful early hospital discharge following myocardial infarction. EUROPEAN HEART JOURNAL Vol.31, () 0195-668X 641-641.
Jones D, Rathod K, Wicks E et al. (2010). Primary percutaneous coronary intervention for ST elevation myocardial infarction in octogenarians. EUROPEAN HEART JOURNAL Vol.31, () 0195-668X 497-498.
Anand DV, Shakur R, Westwood MA et al. (2010). Prospective ECG-triggered high pitch spiral CT coronary angiography provides high image quality at a substantially reduced effective radiation dose. EUROPEAN HEART JOURNAL Vol.31, () 0195-668X 291-292.
Rathod KS, Jones DA, Wicks E et al. (2010). Radial access for primary PCI is associated with excellent long-term outcome and when undertaken selects for low risk cases compared to the femoral approach. EUROPEAN HEART JOURNAL Vol.31, () 0195-668X 769-769.
Rathod K, Jones D, Guttmann O et al. (2010). ST Elevation Myocardial Infarction (STEMI) due to stent thrombosis is associated with worse clinical outcomes than STEMI due to coronary thrombosis. EUROPEAN HEART JOURNAL Vol.31, () 0195-668X 896-896.
Jones DA, Rathod K, Guttmann O et al. (2010). Sex-based differences exist in outcome post acute coronary syndrome (ACS) and vary depending on clinical presentation. EUROPEAN HEART JOURNAL Vol.31, () 0195-668X 365-365.
Jones DA, Rathod K, Akhtar M et al. (2010). COMPARISON OF OUTCOMES OF PATIENTS TREATED WITHIN HOURS VS OUT OF HOURS BY PPCI FOR STEMI. HEART Vol.96, () 1355-6037 A71-A71.
10.1136/hrt.2010.196089.18
Weerackody RP, Burchell T, Mohiddin S et al. (2010). HIGH DOSE ADENOSINE STRESS PERFUSION CARDIOVASCULAR MAGNETIC RESONANCE IMAGING FOR DETECTION OF CORONARY ARTERY DISEASE. HEART Vol.96, () 1355-6037 A46-A46.
10.1136/hrt.2010.195966.26
Wicks EC, Rathod K, Jones D et al. (2010). IMPROVED SURVIVAL WITH ABCIXIMAB IF USED DURING PCI FOR NSTEMI PATIENTS UNDER 75 YEARS OF AGE. HEART Vol.96, () 1355-6037 A23-A24.
10.1136/hrt.2010.195958.13
Jones DA, Wicks E, Gulati A et al. (2010). PRIMARY PERCUTANEOUS CORONARY INTERVENTION FOR ST-ELEVATION MYOCARDIAL INFARCTION IN OCTOGENARIANS. HEART Vol.96, () 1355-6037 A73-A73.
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Jones DA, Rathod K, Guttmann O et al. (2010). ST ELEVATION MYOCARDIAL INFARCTION DUE TO STENT THROMBOSIS IS ASSOCIATED WITH WORSE CLINICAL OUTCOMES THAN STEMI DUE TO CORONARY THROMBOSIS. HEART Vol.96, () 1355-6037 A70-A71.
10.1136/hrt.2010.196089.17
Sharma A, Ramli R, Mohiddin S et al. (2010). THE UTILISATION OF NON-CARDIAC SERVICES BY A HEART ATTACK CENTRE. HEART Vol.96, () 1355-6037 A77-A77.
10.1136/hrt.2010.196113.1
Lovell MJ, Yasin M, Lee KL et al. (2010). Bone marrow mononuclear cells reduce myocardial reperfusion injury by activating the PI3K/Akt survival pathway.. Atherosclerosis Vol.213, (1) 67-76.
10.1016/j.atherosclerosis.2010.07.045
Wong J, Mathur A, Mills PG et al. (2010). Pre-operative ischaemia on CMR stress perfusion is a marker for prolonged post-operative stay after coronary artery bypass grafting. Journal of Cardiovascular Magnetic Resonance Vol.12, (SUPPL. 1) 1097-6647 -.
Mathur A (2009). Endothelial progenitor cells: trick or treat?. Heart Vol.95, (24) 1971-.
10.1136/hrt.2009.174318
Yeo C, Locca D, Wong J et al. (2009). Ejection Fraction and NYHA Class in Heart Failure in the REGENERATE-IHD Stem Cell Study: a Comparison Between the Intramyocardial and Intracoronary Arms. AMERICAN JOURNAL OF CARDIOLOGY Vol.104, (6A) 0002-9149 190D-191D.
Page SP, Mcgill LA, Burchell TR et al. (2009). Fibrosis in left ventricular hypertrophy: cardiac magnetic resonance accurately distinguishes myocardial infarction from myopathic fibrosis. EUROPEAN HEART JOURNAL Vol.30, () 0195-668X 256-256.
Yeo C, Saunders N, Locca D et al. (2009). Ficoll-Paque versus Lymphoprep: a comparative study of two density gradient media for therapeutic bone marrow mononuclear cell preparations.. Regen Med Vol.4, (5) 689-696.
10.2217/rme.09.44
Page SP, Mcgill LA, Burchell TR et al. (2009). Magnetic resonance stress perfusion imaging in patients with left ventricular hypertrophy commonly detects perfusion defects and does not identify coronary disease. EUROPEAN HEART JOURNAL Vol.30, () 0195-668X 550-551.
Yeo C, Locca D, Wong J et al. (2009). EJECTION FRACTION AND NYHA CLASS IN HEART FAILURE IN THE REGENERATE-IHD STEM CELL STUDY: A COMPARISON BETWEEN THE INTRAMYOCARDIAL AND INTRACORONARY ARMS. HEART Vol.95, () 1355-6037 A70-A70.
Flett AS, Westwood MA, Davies LC et al. (2009). The prognostic implications of cardiovascular magnetic resonance.. Circ Cardiovasc Imaging Vol.2, (3) 243-250.
10.1161/CIRCIMAGING.108.840975
Kannan BR, Jain AK, Qureshi SA et al. (2009). Successful exclusion of large post-surgical pseudoaneurysms of the ascending aorta by a percutaneous approach.. Ann Thorac Surg Vol.87, (4) 1281-1284.
10.1016/j.athoracsur.2008.07.053
Yeo C, Mathur A (2009). Autologous bone marrow-derived stem cells for ischemic heart failure: REGENERATE-IHD trial.. Regen Med Vol.4, (1) 119-127.
10.2217/17460751.4.1.119
Martin-Rendon E, Brunskill S, Hyde C et al. (2009). Stem cell therapy for ischaemic heart disease and congestive heart failure. Cochrane Database of Systematic Reviews Vol., (3) 1469-493X -.
Wragg A, Mellad JA, Beltran LE et al. (2008). VEGFR1/CXCR4-positive progenitor cells modulate local inflammation and augment tissue perfusion by a SDF-1-dependent mechanism.. J Mol Med (Berl) Vol.86, (11) 0946-2716 1221-1232.
10.1007/s00109-008-0390-7
Roberts WT, Wright AR, Timmis JB et al. (2008). No difference in diagnostic performance of coronary angiography and CT angiography for stent evaluation when set against IVUS gold-standard. EUROPEAN HEART JOURNAL Vol.29, () 0195-668X 719-719.
Martin-Rendon E, Brunskill SJ, Hyde CJ et al. (2008). Autologous bone marrow stem cells to treat acute myocardial infarction: a systematic review.. Eur Heart J Vol.29, (15) 1807-1818.
10.1093/eurheartj/ehn220
Strange JW, Bucciarelli-Ducci C, Mathur A et al. (2008). Images in cardiovascular medicine. Multiple coronary fistulae: a cause of subendocardial ischemia.. Circulation Vol.117, (6) 853-856.
10.1161/CIRCULATIONAHA.107.725515
Martin-Rendon E, Brunskill S, Dorée C et al. (2008). Stem cell treatment for acute myocardial infarction.. Cochrane Database Syst Rev Vol., (4) CD006536-.
10.1002/14651858.CD006536.pub2
Finlay MC, Ma L, Mathur A et al. (2007). A year's experience of in-stent emergencies - Restenosis is not a benign problem. AMERICAN JOURNAL OF CARDIOLOGY Vol.100, (8A) 0002-9149 197L-198L.
Jain AK, Mathur A (2007). Update on drug-eluting stents: as good as it gets?. Clin Med Vol.7, (4) 1470-2118 401-404.
Koh TW, Mathur A (2007). Coronary stent fracture in a saphenous vein graft to right coronary artery - Successful treatment by the novel use of the Jomed coronary stent graft: Case report and review of tlie literature. INT J CARDIOL Vol.119, (2) 0167-5273 E43-E45.
10.1016/j.ijcard.2007.01.106
Wragg A, Mellad J, San H et al. (2007). Genetic lineage tracking of haematopietic cells using the Cre/Lox system to investigate the role of endothelial progenitor cells in normal vascular development and after vascular injury in mice. HEART Vol.93, () 1355-6037 A98-A99.
Martin-Rendon E, Brunskill S, Doree C et al. (2007). Stem cell treatment for acute myocardial infarction. Cochrane Database of Systematic Reviews Vol., (2) 1469-493X -.
Astroulakis Z, Mathur A (2006). Images in cardiovascular medicine. Percutaneous intervention to a right coronary artery vein graft complicated by perforation into the right heart.. Circulation Vol.114, (17) e549-e550.
10.1161/CIRCULATIONAHA.106.626564
Bartunek J, Dimmeler S, Drexler H et al. (2006). The consensus of the task force of the European Society of Cardiology concerning the clinical investigation of the use of autologous adult stem cells for repair of the heart. EUR HEART J Vol.27, (11) 0195-668X 1338-1340.
10.1093/eurheartj.ehi793
Graham C, Hong S, Mathur A et al. (2006). Bone marrow derived multi-potent progenitor cells augment perfusion of ischaemic tissues via paracrine mechanisms rather than by endothelial differentiation. HEART Vol.92, () 1355-6037 A90-A90.
Lovell M, McDonald M, Sivarajah A et al. (2006). Bone marrow mononuclear cells home to the heart in the acute setting of myocardial infarction with no adverse effects on cardiac function. HEART Vol.92, () 1355-6037 A70-A71.
Smith E, Jain A, DePalma R et al. (2006). Facilitation with abciximab compensates for delays in transfer for primary percutaneous intervention. HEART Vol.92, () 1355-6037 A5-A5.
Lovell M, McDonald M, Sivarajah A et al. (2006). Localisation of bone marrow mononuclear cells administered during acute myocardial infarction; The effects of time in culture. HEART Vol.92, () 1355-6037 A69-A70.
Smith E, Anthony R, Mo R et al. (2006). Myocardial infarction induced by alcohol septal ablation for hypertrophic cardiomyopathy does not activate platelets. HEART Vol.92, () 1355-6037 A96-A97.
Grigoropoulos NF, Mathur A (2006). Stem cells in cardiac repair.. Curr Opin Pharmacol Vol.6, (2) 1471-4892 169-175.
10.1016/j.coph.2005.11.006
Smith EJ, Mo R, Anthony R et al. (2006). Platelet monocyte aggregates determine efficacy of reperfusion following primary percutaneous intervention (PPCI) for ST segment elevation myocardial infarction (STEMI), and are reduced by early anti-platelet therapy. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol.47, (4) 0735-1097 51B-52B.
Astroulakis Z, Mathur A (2006). Percutaneous intervention to a right coronary artery vein graft complicated by perforation into the right heart. Circulation Vol.114, (17) 0009-7322 e549-e550.
Smith EJ, Mathur A, Rothman MT (2005). Recent advances in primary percutaneous intervention for acute myocardial infarction.. Heart Vol.91, (12) 1533-1536.
10.1136/hrt.2005.064493
Harrison P, Mackie I, Mathur A et al. (2005). Platelet hyper-function in acute coronary syndromes.. Blood Coagul Fibrinolysis Vol.16, (8) 0957-5235 557-562.
10.1097/01.mbc.0000187252.09759.ba
Scotland RS, Cohen M, Foster P et al. (2005). C-type natriuretic peptide inhibits leukocyte recruitment and platelet-leukocyte interactions via suppression of P-selectin expression.. Proc Natl Acad Sci U S A Vol.102, (40) 0027-8424 14452-14457.
10.1073/pnas.0504961102
Smith EJ, Jain AK, Shukla SK et al. (2005). Pre hospital ECG diagnosis by ambulance crews reduces time to reperfusion in ST Segment Elevation Myocardial Infarction (STEMI) patients treated with primary angioplasty (PA). HEART Vol.91, () 1355-6037 A23-A23.
Monaco C, Mathur A, Martin JF (2005). What causes acute coronary syndromes? Applying Koch's postulates.. Atherosclerosis Vol.179, (1) 0021-9150 1-15.
10.1016/j.atherosclerosis.2004.10.022
MATHUR A, Lovell MJ, Ginks M (2005). Adult stem cells and their role in the treatment of heart disease. Heart failure & hypertension abstracts Vol.35, () 4-8.
Lovell MJ, Ang R, Mathur A (2005). Models of cardiovascular disease in stem cell research. Drug Discovery Today: Disease Models Vol.2, (3) 1740-6757 239-244.
Harrison P, Mackie I, Mathur A et al. (2005). Platelet hyper-function in acute coronary syndromes.. Blood Coagul Fibrinolysis Vol.16, (8) 557-562.
Mathur A, Martin JF (2004). Stem cells and repair of the heart.. Lancet Vol.364, (9429) 183-192.
10.1016/S0140-6736(04)16632-4
Smith EJ, Keeble TR, Preston MA et al. (2004). Vascular brachytherapy (VBT) for the treatment of instent restenosis (IRS): A single centre UK experience. HEART Vol.90, () 1355-6037 A17-A17.
Foster P, Mathur A, Ahluwalia A (2004). Bradykinin protects against ischemia/reperfusion injury by opening mitochondrial KATP channels in the endothelial cell: a role for nitric oxide. FASEB JOURNAL Vol.18, (4) 0892-6638 A230-A230.
Ahluwalia A, Foster P, Scotland RS et al. (2004). Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment.. Proc Natl Acad Sci U S A Vol.101, (5) 0027-8424 1386-1391.
10.1073/pnas.0304264101
Lovell MJ, Mathur A (2004). The role of stem cells for treatment of cardiovascular disease.. Cell Prolif Vol.37, (1) 0960-7722 67-87.
10.1111/j.1365-2184.2004.00301.x
Mathur A, Hong Y, Wang G et al. (2004). Assays of megakaryocyte development: surface antigen expression, ploidy, and size.. Methods Mol Biol Vol.272, () 309-322.
10.1385/1-59259-782-3:309
Kennon SR, Ahsan S, Mathur A et al. (2003). Intracoronary abciximab delivered via the central lumen of an over the wire balloon for the treatment of no-reflow. AMERICAN JOURNAL OF CARDIOLOGY Vol.92, (6A) 0002-9149 135L-135L.
Barakat K, Kennon S, Mathur A et al. (2003). The influence of vitamin D deficiency and vitamin D receptor polymorphisms on prognosis following non ST elevation acute coronary syndromes. HEART Vol.89, () 1355-6037 A9-A9.
Barakat K, Kennon S, Mathur A et al. (2003). The interleukin 6-174 G > C promoter polymorphism is associated with a poor prognosis following admission with non ST elevation acute coronary syndromes. HEART Vol.89, () 1355-6037 A8-A8.
Foster P, Mathur A, McLean P et al. (2003). Anti-leukocyte properties of a novel non NO-based soluble guanylate cyclase activator, BAY 41-2272. FASEB JOURNAL Vol.17, (5) 0892-6638 A1052-A1052.
Cotton JM, Hong Y, Hawe E et al. (2003). Rise of circulating thrombopoietin following cardiothoracic surgery is potentiated in patients with coronary atherosclerosis: correlation with a preceding increase in levels of interleukin-6.. Thromb Haemost Vol.89, (3) 0340-6245 538-543.
10.1267/THRO03030538
Cotton JM, Hong Y, Hawe E et al. (2003). Rise of circulating thrombopoietin following cardiothoracic surgery is potentiated in patients with coronary atherosclerosis: correlation with a preceding increase in levels of interleukin-6.. Thromb Haemost Vol.89, (3) 538-543.
10.1267/THRO03030538
Cotton JM, Mathur A, Hong Y et al. (2002). Acute rise of circulating vascular endothelial growth factor-A in patients with coronary artery disease following cardiothoracic surgery. EUR HEART J Vol.23, (12) 0195-668X 953-959.
10.1053/euhj.2001.3034
Mohamed-Ali V, Goodrick SJ, Erusalimsky JD et al. (2002). Redox state, mitochondrial membrane potential and UCP expression in relation to lipid content in adipocytes. BIOPHYS J Vol.82, (1) 0006-3495 344A-344A.
Mathur A, Robinson MS, Cotton J et al. (2001). Platelet reactivity in acute coronary syndromes: evidence for differences in platelet behaviour between unstable angina and myocardial infarction.. Thromb Haemost Vol.85, (6) 0340-6245 989-994.
Mathur A, Hong Y, Martin J et al. (2001). Megakaryocytic differentiation is accompanied by a reduction in cell migratory potential.. Br J Haematol Vol.112, (2) 0007-1048 459-465.
10.1046/j.1365-2141.2001.02534.x
Beltran B, Mathur A, Duchen MR et al. (2000). The effect of nitric oxide on cell respiration: A key to understanding its role in cell survival or death. P NATL ACAD SCI USA Vol.97, (26) 0027-8424 14602-14607.
10.1073/pnas.97.26.14602
Mathur A, Hong Y, Kemp BK et al. (2000). Evaluation of fluorescent dyes for the detection of mitochondrial membrane potential changes in cultured cardiomyocytes. Cardiovasc Res Vol.46, (1) 126-138.
Cotton JM, Webb KE, Mathur A et al. (2000). Impact of the -455G>A promoter polymorphism in the B fibrinogen gene on stimulated fibrinogen production following bypass surgery.. Thromb Haemost Vol.84, (5) 926-927.
Zachary I, Mathur A, Yla-Herttuala S et al. (2000). Vascular protection: A novel nonangiogenic cardiovascular role for vascular endothelial growth factor. Arterioscler Thromb Vasc Biol Vol.20, (6) 1512-1520.
Martin JF, Smith RE, Mathur A (1999). Endogenous mediators and thrombophilia. Baillieres Best Pract Res Clin Haematol Vol.12, (3) 373-386.
Genever PG, Wilkinson DJ, Patton AJ et al. (1999). Expression of a functional N-methyl-D-aspartate-type glutamate receptor by bone marrow megakaryocytes. Blood Vol.93, (9) 2876-2883.

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Dr Anthony Mathur, MD, Phd, FRCP
Clinical Senior Lecturer
William Harvey Research Institute
Centre for Clinical Pharmacology
Barts and the London
Queen Mary's School of Medicine and Dentistry
Charterhouse Square
London, WC1M 6BQ
T: +44 (0) 20 7882 5906
T: +44(0)  20 8983 2448
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