HomeContact: s.e.petersen@qmul.ac.uk
Steffen Petersen graduated in 1998 in Mainz in Germany. From 1998 until 2002 he worked as a Cardiology Registrar at the University Hospital Mainz with a major research interest in the field of Cardiovascular Magnetic Resonance. Supported by grants from the German Academic Exchange Service and the British Heart Foundation he joined the Cardiovascular MR group at the University of Oxford set up by Prof Stefan Neubauer (OCMR) and received his DPhil in 2005 entitled “Insights into cardiac remodelling by multi-modal magnetic resonance imaging and spectroscopy”. He then finished his Cardiology training and continued his research interests as a clinical lecturer in the Department of Cardiovascular Medicine at the University of Oxford/John Radcliffe Hospital. Following his CCT in Cardiology in autumn 2009 his took up his current position as Reader in Cardiovascular Imaging and Centre Lead in the new Advanced Cardiovascular Imaging Centre funded through the NIHR Cardiovascular Biomedical Research Unit.
Current research interests
My long-term aim is to build an internationally leading translational cardiovascular research group which will integrate cardiovascular MR, echo, PET-CT and cardiac CT.
CV BRU themes with cardiovascular imaging research:
- Cardiovascular stem cell therapy
- Ischaemia reperfusion injury in acute coronary syndromes
- Dietary nitrate in hypertension and vasoprotection.
Technical development and application of:
- Vascular imaging: plaque characterisation, vascular function, endothelial function, etc
- Deeper myocardial phenotyping: global and regional function, myocardial fibrosis, myocardial blood flow quantification, etc.
- Use of cardiovascular imaging technology to support early phase clinical trials of cardiovascular therapeutic agents developed at the William Harvey Research Institute.
- Use of large-scale imaging technology in population based studies (e.g. UK Biobank).
Key publications
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Hudsmith LE, Tyler DJ, Emmanuel Y, Petersen SE, Francis JM, Watkins H, Clarke K, Robson MD, Neubauer S. (31)P cardiac magnetic resonance spectroscopy during leg exercise at 3 Tesla. Int J Cardiovasc Imaging. 2009 Aug 21.
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Rider RJ, Francis JM, Ali MK, Petersen SE, Robinson M, Robson, MD, Byrne J, Clarke K, Neubauer S. Beneficial cardiovascular effects of bariatric surgical and dietary weight loss in obesity. J Am Coll Cardiol 2009 Aug 18;54(8):718-26.
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Rider RJ, Francis JM, Ali MK, Byrne J, Clarke K, Neubauer S, Petersen SE. Determinants of Left Ventricular Mass in Obesity; A Cardiovascular Magnetic Resonance Study. J Cardiovasc Magn Reson. 2009 Apr 24;11(1):9.
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Petersen SE, Jerosch-Herold M, Hudsmith LE, Robson MD, Francis JM, Doll HA, Selvanayagam JB, Neubauer S, Watkins H. Evidence for microvascular dysfunction in hypertrophic cardiomyopathy: New insights from multi-parametric magnetic resonance imaging. Circulation 2007;115:2418-2425.
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Petersen SE, Wiesmann F, Hudsmith LE, Robson MD, Francis JM, Selvanayagam JB, Neubauer S, Channon KM. Functional and structural remodeling in elite rowers assessed by cardiovascular magnetic resonance: Evidence for desensitization of vascular nitiric oxide signaling. J Am Coll Cardiol 2006;48(4):790-7.
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Petersen SE, Hudsmith LE, Robson MD, Doll HA, Francis JM, Wiesmann F, Jung BA, Hennig J, Watkins H, Neubauer S. Sex-specific characteristics of cardiac function, geometry and mass in young adult elite athletes. J Magn Reson Imaging. 2006;24(2):297-303.
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Petersen SE, Jung BA, Wiesmann F, Selvanayagam JB, Francis JM, Hennig J, Neubauer S, Robson MD. Myocardial tissue phase mapping with cine phase-contrast mr imaging: regional wall motion analysis in healthy volunteers. Radiology 2006;238:816-26.
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Selvanayagam JB, Porto I, Channon K, Petersen SE, Francis JM, Neubauer S, Banning AP. Troponin elevation after percutaneous coronary intervention directly represents the extent of irreversible myocardial injury: insights from cardiovascular magnetic resonance imaging. Circulation. 2005;111:1027-32.
